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Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells - possibilities and current limitations

BACKGROUND: Retinal organoids serve as excellent human-specific disease models for conditions affecting otherwise inaccessible retinal tissue from patients. They permit the isolation of key cell types affected in various eye diseases including retinal ganglion cells (RGCs) and Müller glia. AIM: To r...

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Detalles Bibliográficos
Autores principales: Freude, Kristine Karla, Saruhanian, Sarkis, McCauley, Alanna, Paterson, Colton, Odette, Madeleine, Oostenink, Annika, Hyttel, Poul, Gillies, Mark, Haukedal, Henriette, Kolko, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596448/
https://www.ncbi.nlm.nih.gov/pubmed/33178399
http://dx.doi.org/10.4252/wjsc.v12.i10.1171