Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation

Human pluripotent stem cells (hPSCs) have promising therapeutic applications due to their infinite capacity for self-renewal and pluripotency. Genomic stability is imperative for the clinical use of hPSCs; however, copy number variation (CNV), especially recurrent CNV at 20q11.21, may contribute gen...

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Detalles Bibliográficos
Autores principales: Jo, Hye-Yeong, Lee, Youngsun, Ahn, Hongryul, Han, Hyeong-Jun, Kwon, Ara, Kim, Bo-Young, Ha, Hye-Yeong, Kim, Sang Cheol, Kim, Jung-Hyun, Kim, Yong-Ou, Kim, Sun, Koo, Soo Kyung, Park, Mi-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596514/
https://www.ncbi.nlm.nih.gov/pubmed/33122739
http://dx.doi.org/10.1038/s41598-020-75657-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596514/
https://www.ncbi.nlm.nih.gov/pubmed/33122739
http://dx.doi.org/10.1038/s41598-020-75657-7

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