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Bioanalysis of doxorubicin aglycone metabolites in human plasma samples–implications for doxorubicin drug monitoring

The widespread clinical use of the cytostatic doxorubicin together with the induction of chronic cardiomyopathy necessitates the conduct of further pharmacokinetic trials. Novel analytical technologies suitable for point-of-care applications can facilitate drug level analyses but might be prone to i...

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Detalles Bibliográficos
Autores principales: Siebel, Christian, Lanvers-Kaminsky, Claudia, Würthwein, Gudrun, Hempel, Georg, Boos, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596548/
https://www.ncbi.nlm.nih.gov/pubmed/33122763
http://dx.doi.org/10.1038/s41598-020-75662-w