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Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α

Oestrogen receptor-α (ERα) shuttles continuously between the nucleus and the cytoplasm, and functions as an oestrogen-dependent transcription factor in the nucleus and as an active mediator of signalling pathways, such as phosphatidylinositol 3-kinase (PI3K)/AKT, in the cytoplasm. However, little is...

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Detalles Bibliográficos
Autores principales: Moriyama, Tetsuji, Yoneda, Yoshihiro, Oka, Masahiro, Yamada, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596556/
https://www.ncbi.nlm.nih.gov/pubmed/33122699
http://dx.doi.org/10.1038/s41598-020-75631-3