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Modified aptamers as reagents to characterize recombinant human erythropoietin products
Reliable and reproducible monitoring of the conformational state of therapeutic protein products remains an unmet technological need. This need is amplified by the increasing number of biosimilars entering the drug development pipeline as many branded biologics are reaching the end of their market e...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596557/ https://www.ncbi.nlm.nih.gov/pubmed/33122796 http://dx.doi.org/10.1038/s41598-020-75713-2 |