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Modified aptamers as reagents to characterize recombinant human erythropoietin products

Reliable and reproducible monitoring of the conformational state of therapeutic protein products remains an unmet technological need. This need is amplified by the increasing number of biosimilars entering the drug development pipeline as many branded biologics are reaching the end of their market e...

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Detalles Bibliográficos
Autores principales: Jankowski, Wojciech, Lagassé, H. A. Daniel, Chang, William C., McGill, Joseph, Jankowska, Katarzyna I., Gelinas, Amy D., Janjic, Nebojsa, Sauna, Zuben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596557/
https://www.ncbi.nlm.nih.gov/pubmed/33122796
http://dx.doi.org/10.1038/s41598-020-75713-2