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Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer

Ischemia reperfusion injury (IRI) during liver-metastasis resection for treatment of colon cancer may increase the risk of further metastasis. Peroxisome proliferator-activated receptor-γ (PPARγ) activation has been observed to exert a protective effect against IRI and IRI-induced metastasis of hepa...

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Detalles Bibliográficos
Autores principales: Tashiro, Yoshihiko, Nishino, Hiroto, Higuchi, Takashi, Sugisawa, Norihiko, Fukuda, Yasunari, Yamamoto, Jun, Inubushi, Sachiko, Aoki, Takeshi, Murakami, Masahiko, Singh, Shree Ram, Bouvet, Michael, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596558/
https://www.ncbi.nlm.nih.gov/pubmed/33122687
http://dx.doi.org/10.1038/s41598-020-75210-6