Impact of CYP2C19, CYP3A4, ABCB1, and FMO3 genotypes on plasma voriconazole in Thai patients with invasive fungal infections

Voriconazole is the first‐line antifungal choice in the treatment of invasive fungal infections (IFIs). Single nucleotide polymorphisms (SNPs) in drug‐metabolizing and transporter genes may affect voriconazole pharmacokinetics. This study aimed to determine the frequency of the CYP2C19 rs4244285, rs...

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Detalles Bibliográficos
Autores principales: Chuwongwattana, Sumonrat, Jantararoungtong, Thawinee, Prommas, Santirat, Medhasi, Sadeep, Puangpetch, Apichaya, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596670/
https://www.ncbi.nlm.nih.gov/pubmed/33124772
http://dx.doi.org/10.1002/prp2.665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596670/
https://www.ncbi.nlm.nih.gov/pubmed/33124772
http://dx.doi.org/10.1002/prp2.665

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