Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome

Shikonin (SHI) is an anti-inflammatory agent extracted from natural herbs. It is still unknown whether SHI ameliorates lipopolysaccharide (LPS)-induced cardiac dysfunction. This study aims to explore the protective effects of SHI on LPS-induced myocardial injury and its mechanism. The LPS-induced ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Tao, Jiang, Zhong-Biao, Tong, Zhong-Yi, Zhou, Yang, Chai, Xiang-Ping, Xiao, Xian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596688/
https://www.ncbi.nlm.nih.gov/pubmed/33178042
http://dx.doi.org/10.3389/fphys.2020.570441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596688/
https://www.ncbi.nlm.nih.gov/pubmed/33178042
http://dx.doi.org/10.3389/fphys.2020.570441

Ejemplares similares