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Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome

Shikonin (SHI) is an anti-inflammatory agent extracted from natural herbs. It is still unknown whether SHI ameliorates lipopolysaccharide (LPS)-induced cardiac dysfunction. This study aims to explore the protective effects of SHI on LPS-induced myocardial injury and its mechanism. The LPS-induced ca...

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Detalles Bibliográficos
Autores principales:	Guo, Tao, Jiang, Zhong-Biao, Tong, Zhong-Yi, Zhou, Yang, Chai, Xiang-Ping, Xiao, Xian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596688/ https://www.ncbi.nlm.nih.gov/pubmed/33178042 http://dx.doi.org/10.3389/fphys.2020.570441

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