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HIFα independent mechanisms in renal carcinoma cells modulate divergent outcomes in fibronectin assembly mediated by hypoxia and CoCl(2)

Fibronectin (FN) is a core matrix protein that assembles to form a dynamic cellular scaffold, frequently perturbed during oncogenic transformation. Tumor hypoxia, characterized by low oxygen concentrations in the microenvironment of most solid tumors has been shown to accelerate FN assembly in fibro...

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Detalles Bibliográficos
Autores principales: Magdaleno, Carina, Dixon, Leah, Rajasekaran, Narendiran, Varadaraj, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596723/
https://www.ncbi.nlm.nih.gov/pubmed/33122751
http://dx.doi.org/10.1038/s41598-020-75756-5