A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Malaria is a global health concern, and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP). In contrast to th...

Descripción completa

Detalles Bibliográficos
Autores principales: Thai, Elaine, Costa, Giulia, Weyrich, Anna, Murugan, Rajagopal, Oyen, David, Flores-Garcia, Yevel, Prieto, Katherine, Bosch, Alexandre, Valleriani, Angelo, Wu, Nicholas C., Pholcharee, Tossapol, Scally, Stephen W., Wilson, Ian A., Wardemann, Hedda, Julien, Jean-Philippe, Levashina, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596816/
https://www.ncbi.nlm.nih.gov/pubmed/32790871
http://dx.doi.org/10.1084/jem.20200061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596816/
https://www.ncbi.nlm.nih.gov/pubmed/32790871
http://dx.doi.org/10.1084/jem.20200061

Ejemplares similares