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A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Malaria is a global health concern, and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP). In contrast to th...

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Detalles Bibliográficos
Autores principales:	Thai, Elaine, Costa, Giulia, Weyrich, Anna, Murugan, Rajagopal, Oyen, David, Flores-Garcia, Yevel, Prieto, Katherine, Bosch, Alexandre, Valleriani, Angelo, Wu, Nicholas C., Pholcharee, Tossapol, Scally, Stephen W., Wilson, Ian A., Wardemann, Hedda, Julien, Jean-Philippe, Levashina, Elena A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596816/ https://www.ncbi.nlm.nih.gov/pubmed/32790871 http://dx.doi.org/10.1084/jem.20200061

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