Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity

[Image: see text] The human DNA base excision repair enzyme MUTYH (MutY homolog DNA glycosylase) excises undamaged adenine that has been misincorporated opposite the oxidatively damaged 8-oxoG, preventing transversion mutations and serving as an important defense against the deleterious effects of t...

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Detalles Bibliográficos
Autores principales: Zhu, Ru-Yi, Majumdar, Chandrima, Khuu, Cindy, De Rosa, Mariarosaria, Opresko, Patricia L., David, Sheila S., Kool, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596860/
https://www.ncbi.nlm.nih.gov/pubmed/33145410
http://dx.doi.org/10.1021/acscentsci.0c00369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596860/
https://www.ncbi.nlm.nih.gov/pubmed/33145410
http://dx.doi.org/10.1021/acscentsci.0c00369

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