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Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity
[Image: see text] The human DNA base excision repair enzyme MUTYH (MutY homolog DNA glycosylase) excises undamaged adenine that has been misincorporated opposite the oxidatively damaged 8-oxoG, preventing transversion mutations and serving as an important defense against the deleterious effects of t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596860/ https://www.ncbi.nlm.nih.gov/pubmed/33145410 http://dx.doi.org/10.1021/acscentsci.0c00369 |