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Role of a Tyrosine Radical in Human Ceruloplasmin Catalysis

[Image: see text] Multicopper oxidases (MCOs) are a large family of diverse enzymes found in both eukaryotes and prokaryotes that couple one-electron oxidations of various substrates to the four-electron reduction of O(2) to H(2)O, functioning through a set of metallocofactors consisting of one type...

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Detalles Bibliográficos
Autores principales: Tian, Shiliang, Jones, Stephen M., Solomon, Edward I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596862/
https://www.ncbi.nlm.nih.gov/pubmed/33145420
http://dx.doi.org/10.1021/acscentsci.0c00953