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Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial

BACKGROUND: HIV remains a major public health issue, especially in Eastern and Southern Africa. Pre-exposure prophylaxis is highly effective when adhered to, but its effectiveness is limited by cost, user acceptability and uptake. The cost of a non-inferiority phase III trial is likely to be prohibi...

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Detalles Bibliográficos
Autores principales: Nash, S., Dietrich, J., Ssemata, A. S., Herrera, C., O’Hagan, K., Else, L., Chiodi, F., Kelly, C., Shattock, R., Chirenje, M., Lebina, L., Khoo, S., Bekker, L-G, Weiss, H. A., Gray, C., Stranix-Chibanda, L., Kaleebu, P., Seeley, J., Martinson, N., Fox, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596950/
https://www.ncbi.nlm.nih.gov/pubmed/33121503
http://dx.doi.org/10.1186/s13063-020-04760-x