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A new efficient method to detect genetic interactions for lung cancer GWAS

BACKGROUND: Genome-wide association studies (GWAS) have proven successful in predicting genetic risk of disease using single-locus models; however, identifying single nucleotide polymorphism (SNP) interactions at the genome-wide scale is limited due to computational and statistical challenges. We ad...

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Detalles Bibliográficos
Autores principales: Luyapan, Jennifer, Ji, Xuemei, Li, Siting, Xiao, Xiangjun, Zhu, Dakai, Duell, Eric J., Christiani, David C., Schabath, Matthew B., Arnold, Susanne M., Zienolddiny, Shanbeh, Brunnström, Hans, Melander, Olle, Thornquist, Mark D., MacKenzie, Todd A., Amos, Christopher I., Gui, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596958/
https://www.ncbi.nlm.nih.gov/pubmed/33126877
http://dx.doi.org/10.1186/s12920-020-00807-9