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Effectiveness and safety of high dose clopidogrel plus aspirin in ischemic stroke patients with the single CYP2C19 loss-of-function allele: a randomized trial

BACKGROUND: Dual antiplatelet aggregation therapy leads to better outcomes in patients with carotid artery stenosis, intracranial artery stenosis, minor strokes, or transient ischaemic attacks. However, carriers of the CYP2C19 loss-of-function allele may not experience the desired effects. We attemp...

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Detalles Bibliográficos
Autores principales: Wu, Hongliang, Song, Huiqun, Dou, Lianwei, Gao, Bo, Pan, Yan, Dong, Mei, Chen, Qi, Li, Jiazhen, Song, Lixiang, Liu, Chuanyu, Li, Bing, Chu, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596994/
https://www.ncbi.nlm.nih.gov/pubmed/33121452
http://dx.doi.org/10.1186/s12883-020-01974-z