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Effectiveness and safety of high dose clopidogrel plus aspirin in ischemic stroke patients with the single CYP2C19 loss-of-function allele: a randomized trial
BACKGROUND: Dual antiplatelet aggregation therapy leads to better outcomes in patients with carotid artery stenosis, intracranial artery stenosis, minor strokes, or transient ischaemic attacks. However, carriers of the CYP2C19 loss-of-function allele may not experience the desired effects. We attemp...
Autores principales: | Wu, Hongliang, Song, Huiqun, Dou, Lianwei, Gao, Bo, Pan, Yan, Dong, Mei, Chen, Qi, Li, Jiazhen, Song, Lixiang, Liu, Chuanyu, Li, Bing, Chu, Wenzheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596994/ https://www.ncbi.nlm.nih.gov/pubmed/33121452 http://dx.doi.org/10.1186/s12883-020-01974-z |
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