The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation

BACKGROUND: The clonogenic assay is a versatile and frequently used tool to quantify reproductive cell survival in vitro. Current state-of-the-art analysis relies on plating efficiency-based calculations which assume a linear correlation between the number of cells seeded and the number of colonies...

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Detalles Bibliográficos
Autores principales: Brix, Nikko, Samaga, Daniel, Hennel, Roman, Gehr, Katharina, Zitzelsberger, Horst, Lauber, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597001/
https://www.ncbi.nlm.nih.gov/pubmed/33121517
http://dx.doi.org/10.1186/s13014-020-01697-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597001/
https://www.ncbi.nlm.nih.gov/pubmed/33121517
http://dx.doi.org/10.1186/s13014-020-01697-y

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