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The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation
BACKGROUND: The clonogenic assay is a versatile and frequently used tool to quantify reproductive cell survival in vitro. Current state-of-the-art analysis relies on plating efficiency-based calculations which assume a linear correlation between the number of cells seeded and the number of colonies...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597001/ https://www.ncbi.nlm.nih.gov/pubmed/33121517 http://dx.doi.org/10.1186/s13014-020-01697-y |