Cargando…
The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation
BACKGROUND: The clonogenic assay is a versatile and frequently used tool to quantify reproductive cell survival in vitro. Current state-of-the-art analysis relies on plating efficiency-based calculations which assume a linear correlation between the number of cells seeded and the number of colonies...
Autores principales: | Brix, Nikko, Samaga, Daniel, Hennel, Roman, Gehr, Katharina, Zitzelsberger, Horst, Lauber, Kirsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597001/ https://www.ncbi.nlm.nih.gov/pubmed/33121517 http://dx.doi.org/10.1186/s13014-020-01697-y |
Ejemplares similares
-
Release of monocyte migration signals by breast cancer cell lines after ablative and fractionated γ-irradiation
por: Hennel, Roman, et al.
Publicado: (2014) -
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer
por: Kinzel, Linda, et al.
Publicado: (2016) -
Robustness of Clonogenic Assays as a Biomarker for Cancer Cell Radiosensitivity
por: Matsui, Toshiaki, et al.
Publicado: (2019) -
Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data
por: Schnöller, Leon Emanuel, et al.
Publicado: (2023) -
Clonogenic Assay of Gastric Adenocarcinoma Stem Cells: Clonogenic Assay, Stomach Cancer
por: Kim, Hoon Kyo, et al.
Publicado: (1987)