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NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation

Understanding the biology underlying the mechanisms and pathways regulating pancreatic β cell development is necessary to understand the pathology of diabetes mellitus (DM), which is characterized by the progressive reduction in insulin-producing β cell mass. Pluripotent stem cells (PSCs) can potent...

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Detalles Bibliográficos
Autores principales: Aigha, Idil I., Abdelalim, Essam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597038/
https://www.ncbi.nlm.nih.gov/pubmed/33121533
http://dx.doi.org/10.1186/s13287-020-01977-0