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NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation
Understanding the biology underlying the mechanisms and pathways regulating pancreatic β cell development is necessary to understand the pathology of diabetes mellitus (DM), which is characterized by the progressive reduction in insulin-producing β cell mass. Pluripotent stem cells (PSCs) can potent...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597038/ https://www.ncbi.nlm.nih.gov/pubmed/33121533 http://dx.doi.org/10.1186/s13287-020-01977-0 |