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Combination strategies to overcome resistance to the BCL2 inhibitor venetoclax in hematologic malignancies

Venetoclax has been approved by the United States Food and Drug Administration since 2016 as a monotherapy for treating patients with relapsed/refractory chronic lymphocytic leukemia having 17p deletion. It has led to a breakthrough in the treatment of hematologic malignancies in recent years. Howev...

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Detalles Bibliográficos
Autores principales: Yue, XiaoYan, Chen, Qingxiao, He, JingSong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597043/
https://www.ncbi.nlm.nih.gov/pubmed/33292251
http://dx.doi.org/10.1186/s12935-020-01614-z