8q24 clear cell renal cell carcinoma germline variant is associated with VHL mutation status and clinical aggressiveness

BACKGROUND: The four most commonly-mutated genes in clear cell renal cell carcinoma (ccRCC) tumors are BAP1, PBRM1, SETD2 and VHL. And, there are currently 14 known RCC germline variants that have been reproducibly shown to be associated with RCC risk. However, the association of germline genetics w...

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Detalles Bibliográficos
Autores principales: Eckel-Passow, Jeanette E., Yan, Huihuang, Kosel, Matthew L., Serie, Daniel, Decker, Paul A., Jenkins, Robert B., Costello, Brian, Leibovich, Bradley, Ho, Thai H., Parker, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597051/
https://www.ncbi.nlm.nih.gov/pubmed/33121461
http://dx.doi.org/10.1186/s12894-020-00745-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597051/
https://www.ncbi.nlm.nih.gov/pubmed/33121461
http://dx.doi.org/10.1186/s12894-020-00745-9

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