Large Animal Models of Huntington’s Disease: What We Have Learned and Where We Need to Go Next

Genetically modified rodent models of Huntington’s disease (HD) have been especially valuable to our understanding of HD pathology and the mechanisms by which the mutant HTT gene alters physiology. However, due to inherent differences in genetics, neuroanatomy, neurocircuitry and neurophysiology, an...

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Detalles Bibliográficos
Autores principales: Howland, David, Ellederova, Zdenka, Aronin, Neil, Fernau, Deborah, Gallagher, Jill, Taylor, Amanda, Hennebold, Jon, Weiss, Alison R., Gray-Edwards, Heather, McBride, Jodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597371/
https://www.ncbi.nlm.nih.gov/pubmed/32925082
http://dx.doi.org/10.3233/JHD-200425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597371/
https://www.ncbi.nlm.nih.gov/pubmed/32925082
http://dx.doi.org/10.3233/JHD-200425

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