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Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis

Inhibitors of mitochondrial respiration and ATP synthesis may promote the selective killing of respiration-competent cancer cells that are critical for tumor progression. We previously reported that CADD522, a small molecule inhibitor of the RUNX2 transcription factor, has potential for breast cance...

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Detalles Bibliográficos
Autores principales: Kim, Myoung Sook, Gernapudi, Ramkishore, Cedeño, Yessenia Cedeño, Polster, Brian M., Martinez, Ramon, Shapiro, Paul, Kesari, Santosh, Nurmemmedov, Elmar, Passaniti, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597410/
https://www.ncbi.nlm.nih.gov/pubmed/33196708
http://dx.doi.org/10.18632/oncotarget.27743