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Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis
Inhibitors of mitochondrial respiration and ATP synthesis may promote the selective killing of respiration-competent cancer cells that are critical for tumor progression. We previously reported that CADD522, a small molecule inhibitor of the RUNX2 transcription factor, has potential for breast cance...
Autores principales: | Kim, Myoung Sook, Gernapudi, Ramkishore, Cedeño, Yessenia Cedeño, Polster, Brian M., Martinez, Ramon, Shapiro, Paul, Kesari, Santosh, Nurmemmedov, Elmar, Passaniti, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597410/ https://www.ncbi.nlm.nih.gov/pubmed/33196708 http://dx.doi.org/10.18632/oncotarget.27743 |
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