The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging

Aging is associated with metabolic changes and low-grade inflammation in several organs, which may be due to NLRP3 inflammasome activation. Methods: Here, we asked whether age-related liver changes such as lipid metabolism and fibrosis are reduced in aged mice lacking the NLRP3 inflammasome. We repo...

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Detalles Bibliográficos
Autores principales: Gallego, Paloma, Castejón-Vega, Beatriz, del Campo, José A., Cordero, Mario D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598267/
https://www.ncbi.nlm.nih.gov/pubmed/32977490
http://dx.doi.org/10.3390/cells9102148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598267/
https://www.ncbi.nlm.nih.gov/pubmed/32977490
http://dx.doi.org/10.3390/cells9102148

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