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Sphingolipid Metabolism in Glioblastoma and Metastatic Brain Tumors: A Review of Sphingomyelinases and Sphingosine-1-Phosphate

Glioblastoma (GBM) is a primary malignant brain tumor with a dismal prognosis, partially due to our inability to completely remove and kill all GBM cells. Rapid tumor recurrence contributes to a median survival of only 15 months with the current standard of care which includes maximal surgical resec...

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Detalles Bibliográficos
Autores principales: Hawkins, Cyntanna C., Ali, Tomader, Ramanadham, Sasanka, Hjelmeland, Anita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598277/
https://www.ncbi.nlm.nih.gov/pubmed/32977496
http://dx.doi.org/10.3390/biom10101357