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Sphingolipid Metabolism in Glioblastoma and Metastatic Brain Tumors: A Review of Sphingomyelinases and Sphingosine-1-Phosphate
Glioblastoma (GBM) is a primary malignant brain tumor with a dismal prognosis, partially due to our inability to completely remove and kill all GBM cells. Rapid tumor recurrence contributes to a median survival of only 15 months with the current standard of care which includes maximal surgical resec...
Autores principales: | Hawkins, Cyntanna C., Ali, Tomader, Ramanadham, Sasanka, Hjelmeland, Anita B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598277/ https://www.ncbi.nlm.nih.gov/pubmed/32977496 http://dx.doi.org/10.3390/biom10101357 |
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