Chitosan Hydrogel Doped with PEG-PLA Nanoparticles for the Local Delivery of miRNA-146a to Treat Allergic Rhinitis

To prepare a binary formulation delivering miRNA-146 and evaluate a nucleic acid nasal delivery system by investigating its pharmacodynamic effects in allergic rhinitis. The gel/NPs/miR-146a thermosensitive in situ chitosan hydrogel carrying a nucleic acid was prepared and evaluated for its characte...

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Detalles Bibliográficos
Autores principales: Su, Yu, Sun, Bixi, Gao, Xiaoshu, Liu, Shuwen, Hao, Rubin, Han, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598290/
https://www.ncbi.nlm.nih.gov/pubmed/32977497
http://dx.doi.org/10.3390/pharmaceutics12100907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598290/
https://www.ncbi.nlm.nih.gov/pubmed/32977497
http://dx.doi.org/10.3390/pharmaceutics12100907

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