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Molecular Pathogenesis of Pancreatic Ductal Adenocarcinoma: Impact of miR-30c-5p and miR-30c-2-3p Regulation on Oncogenic Genes

SIMPLE SUMMARY: A total of 10 genes (YWHAZ, F3, TMOD3, NFE2L3, ENDOD1, ITGA3, RRAS, PRSS23, TOP2A, and LRRFIP1) were identified as tumor suppressive miR-30c-5p and miR-30c-2-3p targets in pancreatic ductal adenocarcinoma (PDAC), and expression of these genes were independent prognostic factors for p...

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Detalles Bibliográficos
Autores principales: Tanaka, Takako, Okada, Reona, Hozaka, Yuto, Wada, Masumi, Moriya, Shogo, Satake, Souichi, Idichi, Tetsuya, Kurahara, Hiroshi, Ohtsuka, Takao, Seki, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598296/
https://www.ncbi.nlm.nih.gov/pubmed/32977589
http://dx.doi.org/10.3390/cancers12102731