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A needle in the haystack? Assessing the significance of envelope (E) gene-negative, nucleocapsid (N2) gene-positive SARS-CoV-2 detection by the Cepheid Xpert Xpress SARS-COV-2 assay

The clinical significance of high crossing threshold (Ct) detection of SARS-CoV-2 by RT-PCR is inadequately defined. In the course of universal admission screening with the Cepheid Xpert Xpress SARS-CoV-2 assay at our institution, we observed that 3.9 % (44/1123) of SARS-CoV-2 positive results were...

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Detalles Bibliográficos
Autores principales: Khoshchehreh, Mahdi, Wald-Dickler, Noah, Holtom, Paul, Butler-Wu, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598560/
https://www.ncbi.nlm.nih.gov/pubmed/33142250
http://dx.doi.org/10.1016/j.jcv.2020.104683