Catalpol Ameliorates Insulin Sensitivity and Mitochondrial Respiration in Skeletal Muscle of Type-2 Diabetic Mice Through Insulin Signaling Pathway and AMPK/SIRT1/PGC-1α/PPAR-γ Activation

Catalpol was tested for various disorders including diabetes mellitus. Numerous molecular mechanisms have emerged supporting its biological effects but with little information towards its insulin sensitizing effect. In this study, we have investigated its effect on skeletal muscle mitochondrial resp...

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Detalles Bibliográficos
Autores principales: Yap, Kah Heng, Yee, Gan Sook, Candasamy, Mayuren, Tan, Swee Ching, Md, Shadab, Abdul Majeed, Abu Bakar, Bhattamisra, Subrat Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598587/
https://www.ncbi.nlm.nih.gov/pubmed/32987623
http://dx.doi.org/10.3390/biom10101360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598587/
https://www.ncbi.nlm.nih.gov/pubmed/32987623
http://dx.doi.org/10.3390/biom10101360

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