Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma

SIMPLE SUMMARY: The identification of new pharmacological combinations with synergistic effect in multiple myeloma is highly relevant since this is, for the moment, an incurable disease. The high expression of Proviral Insertion site for Moloney murine leukemia virus (PIM) kinases, especially PIM2,...

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Detalles Bibliográficos
Autores principales: Paíno, Teresa, González-Méndez, Lorena, San-Segundo, Laura, Corchete, Luis A., Hernández-García, Susana, Díaz-Tejedor, Andrea, Algarín, Esperanza M., Mogollón, Pedro, Martín-Sánchez, Montserrat, Gutiérrez, Norma C., Mateos, María-Victoria, Garayoa, Mercedes, Ocio, Enrique M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598606/
https://www.ncbi.nlm.nih.gov/pubmed/32987735
http://dx.doi.org/10.3390/cancers12102743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598606/
https://www.ncbi.nlm.nih.gov/pubmed/32987735
http://dx.doi.org/10.3390/cancers12102743

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