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Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals

Human immunodeficiency virus 1 (HIV-1) is the most prevalent human retrovirus. Recent data show that 34 million people are living with HIV-1 worldwide. HIV-1 infections can lead to AIDS which still causes nearly 20,000 deaths annually in the USA alone. As this retrovirus leads to high morbidity and...

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Detalles Bibliográficos
Autores principales: Sampey, Gavin C., Iordanskiy, Sergey, Pleet, Michelle L., DeMarino, Catherine, Romerio, Fabio, Mahieux, Renaud, Kashanchi, Fatah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598649/
https://www.ncbi.nlm.nih.gov/pubmed/32977702
http://dx.doi.org/10.3390/v12101067