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Zebrafish Oxr1a Knockout Reveals Its Role in Regulating Antioxidant Defenses and Aging

Oxidation resistance gene 1 (OXR1) is essential for protection against oxidative stress in mammals, but its functions in non-mammalian vertebrates, especially in fish, remain uncertain. Here, we created a homozygous oxr1a-knockout zebrafish via the CRISPR/Cas9 (Clustered Regularly Interspaced Short...

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Detalles Bibliográficos
Autores principales: Xu, Hao, Jiang, Yu, Li, Sheng, Xie, Lang, Tao, Yi-Xi, Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598701/
https://www.ncbi.nlm.nih.gov/pubmed/32987694
http://dx.doi.org/10.3390/genes11101118