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Characterization of Hematopoiesis in Sickle Cell Disease by Prospective Isolation of Stem and Progenitor Cells

The consequences of sickle cell disease (SCD) include ongoing hematopoietic stress, hemolysis, vascular damage, and effect of chronic therapies, such as blood transfusions and hydroxyurea, on hematopoietic stem and progenitor cell (HSPC) have been poorly characterized. We have quantified the frequen...

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Detalles Bibliográficos
Autores principales: Tolu, Seda S., Wang, Kai, Yan, Zi, Zhang, Shouping, Roberts, Karl, Crouch, Andrew S., Sebastian, Gracy, Chaitowitz, Mark, Fornari, Eric D., Schwechter, Evan M., Uehlinger, Joan, Manwani, Deepa, Minniti, Caterina P., Bouhassira, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598721/
https://www.ncbi.nlm.nih.gov/pubmed/32987729
http://dx.doi.org/10.3390/cells9102159