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Complement activation and endothelial perturbation parallel COVID-19 severity and activity

BACKGROUND: Animal models and few clinical reports suggest the involvement of the complement system in the onset of severe manifestations of coronavirus disease-2019 (COVID-19). However, complement contribution to endotheliopathy and hypercoagulability has not been elucidated yet. OBJECTIVE: To eval...

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Detalles Bibliográficos
Autores principales: Cugno, Massimo, Meroni, Pier Luigi, Gualtierotti, Roberta, Griffini, Samantha, Grovetti, Elena, Torri, Adriana, Lonati, Paola, Grossi, Claudia, Borghi, Maria Orietta, Novembrino, Cristina, Boscolo, Massimo, Uceda Renteria, Sara Colonia, Valenti, Luca, Lamorte, Giuseppe, Manunta, Maria, Prati, Daniele, Pesenti, Antonio, Blasi, Francesco, Costantino, Giorgio, Gori, Andrea, Bandera, Alessandra, Tedesco, Francesco, Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598768/
https://www.ncbi.nlm.nih.gov/pubmed/33139116
http://dx.doi.org/10.1016/j.jaut.2020.102560