Cargando…
The synergy of damage repair and retention promotes rejuvenation and prolongs healthy lifespans in cell lineages
Damaged proteins are inherited asymmetrically during cell division in the yeast Saccharomyces cerevisiae, such that most damage is retained within the mother cell. The consequence is an ageing mother and a rejuvenated daughter cell with full replicative potential. Daughters of old and damaged mother...
Autores principales: | Schnitzer, Barbara, Borgqvist, Johannes, Cvijovic, Marija |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598927/ https://www.ncbi.nlm.nih.gov/pubmed/33044956 http://dx.doi.org/10.1371/journal.pcbi.1008314 |
Ejemplares similares
-
Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing
por: Borgqvist, Johannes, et al.
Publicado: (2020) -
The choice of the objective function in flux balance analysis is crucial for predicting replicative lifespans in yeast
por: Schnitzer, Barbara, et al.
Publicado: (2022) -
Symmetry structures in dynamic models of biochemical systems
por: Ohlsson, Fredrik, et al.
Publicado: (2020) -
Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing instability
por: Borgqvist, Johannes, et al.
Publicado: (2021) -
Robustness of Nutrient Signaling Is Maintained by Interconnectivity Between Signal Transduction Pathways
por: Welkenhuysen, Niek, et al.
Publicado: (2019)