Longevity genes, cardiac ageing, and the pathogenesis of cardiomyopathy: implications for understanding the effects of current and future treatments for heart failure

The two primary molecular regulators of lifespan are sirtuin-1 (SIRT1) and mammalian target of rapamycin complex 1 (mTORC1). Each plays a central role in two highly interconnected pathways that modulate the balance between cellular growth and survival. The activation of SIRT1 [along with peroxisome...

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Detalles Bibliográficos
Autor principal: Packer, Milton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599035/
https://www.ncbi.nlm.nih.gov/pubmed/32460327
http://dx.doi.org/10.1093/eurheartj/ehaa360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599035/
https://www.ncbi.nlm.nih.gov/pubmed/32460327
http://dx.doi.org/10.1093/eurheartj/ehaa360

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