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M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity

A greater understanding of hematopoietic stem cell (HSC) regulation is required for dissecting protective versus detrimental immunity to pathogens that cause chronic infections such as Mycobacterium tuberculosis (Mtb). We have shown that systemic administration of Bacille Calmette-Guérin (BCG) or β-...

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Detalles Bibliográficos
Autores principales: Khan, Nargis, Downey, Jeffrey, Sanz, Joaquin, Kaufmann, Eva, Blankenhaus, Birte, Pacis, Alain, Pernet, Erwan, Ahmed, Eisha, Cardoso, Silvia, Nijnik, Anastasia, Mazer, Bruce, Sassetti, Christopher, Behr, Marcel A., Soares, Miguel P., Barreiro, Luis B., Divangahi, Maziar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599081/
https://www.ncbi.nlm.nih.gov/pubmed/33125891
http://dx.doi.org/10.1016/j.cell.2020.09.062