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Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyrosine kinases that regulate innate immune responses and CNS...

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Detalles Bibliográficos
Autores principales: DuBois, Juwen C., Ray, Alex K., Davies, Peter, Shafit-Zagardo, Bridget
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599105/
https://www.ncbi.nlm.nih.gov/pubmed/33121494
http://dx.doi.org/10.1186/s12974-020-01982-3