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Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
BACKGROUND: Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyrosine kinases that regulate innate immune responses and CNS...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599105/ https://www.ncbi.nlm.nih.gov/pubmed/33121494 http://dx.doi.org/10.1186/s12974-020-01982-3 |