Cargando…

Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyrosine kinases that regulate innate immune responses and CNS...

Descripción completa

Detalles Bibliográficos
Autores principales:	DuBois, Juwen C., Ray, Alex K., Davies, Peter, Shafit-Zagardo, Bridget
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599105/ https://www.ncbi.nlm.nih.gov/pubmed/33121494 http://dx.doi.org/10.1186/s12974-020-01982-3

Ejemplares similares

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis
por: Weinger, Jason G, et al.
Publicado: (2011)

Akt3-Mediated Protection Against Inflammatory Demyelinating Disease
por: DuBois, Juwen C., et al.
Publicado: (2019)

Mechanism of gut microbiota and Axl/SOCS3 in experimental autoimmune encephalomyelitis
por: Li, Xiao-Ling, et al.
Publicado: (2019)

TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury
por: Shafit-Zagardo, Bridget, et al.
Publicado: (2023)

Role of Anti-Osteopontin Antibodies in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
por: Clemente, Nausicaa, et al.
Publicado: (2017)

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination
por: Tsiperson, Vladislav, et al.
Publicado: (2010)

Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms
por: Moransard, M., et al.
Publicado: (2017)

Anti-IL-17A blocking antibody reduces cyclosporin A-induced relapse in experimental autoimmune encephalomyelitis mice
por: Saitoh, Kodai, et al.
Publicado: (2016)

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
Publicado: (1995)

Treatment with the Antipsychotic Agent, Risperidone, Reduces Disease Severity in Experimental Autoimmune Encephalomyelitis
por: O'Sullivan, David, et al.
Publicado: (2014)

Chloroquine Treatment Enhances Regulatory T Cells and Reduces the Severity of Experimental Autoimmune Encephalomyelitis
por: Thomé, Rodolfo, et al.
Publicado: (2013)

Sterol Regulatory Element Binding Protein (Srb1) Is Required for Hypoxic Adaptation and Virulence in the Dimorphic Fungus Histoplasma capsulatum
por: DuBois, Juwen C., et al.
Publicado: (2016)

The Anti-Inflammatory Effect of Sulforaphane in Mice with Experimental Autoimmune Encephalomyelitis
por: Yoo, Il-Han, et al.
Publicado: (2019)

Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy
por: Mocholi, Enric, et al.
Publicado: (2018)

Lactobacillus reuteri Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota
por: He, Baokun, et al.
Publicado: (2019)

Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine
por: Paris, Daniel, et al.
Publicado: (2013)

Environmental Influences in Experimental Autoimmune Encephalomyelitis
por: Constantinescu, Cris S
Publicado: (2005)

Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
por: Robichon, Katharina, et al.
Publicado: (2020)

Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis
por: Luo, Lin, et al.
Publicado: (2021)

MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated
por: Flytzani, Sevasti, et al.
Publicado: (2015)

Anti-IL-6 Receptor Antibody Inhibits Spontaneous Pain at the Pre-onset of Experimental Autoimmune Encephalomyelitis in Mice
por: Serizawa, Kenichi, et al.
Publicado: (2019)

Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
por: Shin, Taekyun, et al.
Publicado: (2012)

Tuftsin Promotes an Anti-Inflammatory Switch and Attenuates Symptoms in Experimental Autoimmune Encephalomyelitis
por: Wu, Muzhou, et al.
Publicado: (2012)

The Anti-Inflammatory Effects of Oral-Formulated Tacrolimus in Mice with Experimental Autoimmune Encephalomyelitis
por: Kim, Myung-Jin, et al.
Publicado: (2017)

Gas6 enhances axonal ensheathment by MBP(+) membranous processes in human DRG/OL promyelinating co-cultures
por: O’Guin, Kathleen N., et al.
Publicado: (2014)

Angiogenesis in multiple sclerosis and experimental autoimmune encephalomyelitis
por: Girolamo, Francesco, et al.
Publicado: (2014)

Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
por: Basler, Michael, et al.
Publicado: (2014)

Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis
por: Lutz, Sarah E., et al.
Publicado: (2013)

The Role of ERK Signaling in Experimental Autoimmune Encephalomyelitis
por: Birkner, Katharina, et al.
Publicado: (2017)

Amelioration of experimental autoimmune encephalomyelitis by Ishige okamurae
por: Ahn, Meejung, et al.
Publicado: (2018)

Oryeongsan (Goreisan) Ameliorates Experimental Autoimmune Encephalomyelitis
por: Inada, Rino, et al.
Publicado: (2019)

Opposing T Cell Responses in Experimental Autoimmune Encephalomyelitis
por: Saligrama, Naresha, et al.
Publicado: (2019)

Molecular effects of curcumin on the experimental autoimmune encephalomyelitis
por: Mavaddatiyan, Laleh, et al.
Publicado: (2021)

Immunomodulatory therapy with glatiramer acetate reduces endoplasmic reticulum stress and mitochondrial dysfunction in experimental autoimmune encephalomyelitis
por: Makar, Tapas K., et al.
Publicado: (2023)

Localization of near-infrared labeled antibodies to the central nervous system in experimental autoimmune encephalomyelitis
por: Lee, Sangmin, et al.
Publicado: (2019)

MicroRNAs as disease progression biomarkers and therapeutic targets in experimental autoimmune encephalomyelitis model of multiple sclerosis
por: Martinez, Bridget, et al.
Publicado: (2020)

RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis
por: Lee, Jae-Kyung, et al.
Publicado: (2016)

Rituximab Therapy Reduces Organ-Specific T Cell Responses and Ameliorates Experimental Autoimmune Encephalomyelitis
por: Monson, Nancy L., et al.
Publicado: (2011)

A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis
por: Calvo-Barreiro, Laura, et al.
Publicado: (2020)

Graphene Oxide Nanosheets Reduce Astrocyte Reactivity to Inflammation and Ameliorate Experimental Autoimmune Encephalomyelitis
por: Di Mauro, Giuseppe, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_d8l1pl8uq4ml0k3cf68vqfpjbi