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Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis

BACKGROUND: Multiple sclerosis is an immune-mediated disease of the central nervous system (CNS) characterized by inflammation, oligodendrocytes loss, demyelination, and damaged axons. Tyro3, Axl, and MerTK belong to a family of receptor tyrosine kinases that regulate innate immune responses and CNS...

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Detalles Bibliográficos
Autores principales:	DuBois, Juwen C., Ray, Alex K., Davies, Peter, Shafit-Zagardo, Bridget
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599105/ https://www.ncbi.nlm.nih.gov/pubmed/33121494 http://dx.doi.org/10.1186/s12974-020-01982-3

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