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Induction of protein aggregation and starvation response by tRNA modification defects

Posttranscriptional modifications of anticodon loops contribute to the decoding efficiency of tRNAs by supporting codon recognition and loop stability. Consistently, strong synthetic growth defects are observed in yeast strains simultaneously lacking distinct anticodon loop modifications. These phen...

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Detalles Bibliográficos
Autores principales: Klassen, Roland, Bruch, Alexander, Schaffrath, Raffael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599136/
https://www.ncbi.nlm.nih.gov/pubmed/32860511
http://dx.doi.org/10.1007/s00294-020-01103-w