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Prevention of unwanted recombination at damaged replication forks

Homologous recombination is essential for the maintenance of genome integrity but must be strictly controlled to avoid dangerous outcomes that produce the opposite effect, genomic instability. During unperturbed chromosome replication, recombination is globally inhibited at ongoing DNA replication f...

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Detalles Bibliográficos
Autores principales: Lehmann, Carl P., Jiménez-Martín, Alberto, Branzei, Dana, Tercero, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599154/
https://www.ncbi.nlm.nih.gov/pubmed/32671464
http://dx.doi.org/10.1007/s00294-020-01095-7