Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue

The disease-associated nuclease–helicase DNA2 has been implicated in DNA end-resection during DNA double-strand break repair, Okazaki fragment processing, and the recovery of stalled DNA replication forks (RFs). Its role in Okazaki fragment processing has been proposed to explain why DNA2 is indispe...

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Detalles Bibliográficos
Autores principales: Appanah, Rowin, Jones, David, Falquet, Benoît, Rass, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599155/
https://www.ncbi.nlm.nih.gov/pubmed/32909097
http://dx.doi.org/10.1007/s00294-020-01106-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599155/
https://www.ncbi.nlm.nih.gov/pubmed/32909097
http://dx.doi.org/10.1007/s00294-020-01106-7

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