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Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue
The disease-associated nuclease–helicase DNA2 has been implicated in DNA end-resection during DNA double-strand break repair, Okazaki fragment processing, and the recovery of stalled DNA replication forks (RFs). Its role in Okazaki fragment processing has been proposed to explain why DNA2 is indispe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599155/ https://www.ncbi.nlm.nih.gov/pubmed/32909097 http://dx.doi.org/10.1007/s00294-020-01106-7 |