A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis

During mitosis, translation of most mRNAs is strongly repressed; none of the several explanatory hypotheses suggested can fully explain the molecular basis of this phenomenon. Here we report that cyclin-dependent CDK11/p58—a serine/threonine kinase abundantly expressed during M phase—represses overa...

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Detalles Bibliográficos
Autores principales: An, Sihyeon, Kwon, Oh Sung, Yu, Jinbae, Jang, Sung Key
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599166/
https://www.ncbi.nlm.nih.gov/pubmed/32030451
http://dx.doi.org/10.1007/s00018-019-03436-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599166/
https://www.ncbi.nlm.nih.gov/pubmed/32030451
http://dx.doi.org/10.1007/s00018-019-03436-3

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